Novel Magnetic Resonance Imaging Tools for the Diagnosis of Degenerative Disc Disease: A Narrative Review

Novel Magnetic Resonance Imaging Tools for the Diagnosis of Degenerative Disc Disease: A Narrative Review

Blog Article

Low back pain (LBP) is one of 09gi shades eq the leading causes of disability worldwide, with a significant socioeconomic burden on healthcare systems.It is mainly caused by degenerative disc disease (DDD), a progressive, chronic, and age-related process.With its capacity to accurately characterize intervertebral disc (IVD) and spinal morphology, magnetic resonance imaging (MRI) has been established as one of the most valuable tools in diagnosing DDD.However, existing technology cannot detect subtle changes in IVD tissue composition and cell metabolism.In this review, we summarized the state of the art regarding innovative quantitative MRI modalities that have shown the capacity to discriminate and quantify changes in matrix composition and integrity, as well as biomechanical changes in the early stages of DDD.

Validation and implementation of this new technology in hp 15-ef1005ds the clinical setting will allow for an early diagnosis of DDD and ideally guide conservative and regenerative treatments that may prevent the progression of the degenerative process rather than intervene at the latest stages of the disease.